Hyponatremia

Follow Most common electrolyte disorder in clinical practice. Disturbance in sodium-water balance. Skilled management is essential – Hyponatremia can be life threatening – Inappropriate therapy can be deleterious. Hyponatremia can be a contributing factor to morbidity and death in hospitalized patients. Serum Na = Total body sodium / Total body water Hyponatremia could be due to 1. Increase in body water 2. Decrease in body sodium 3. Both Remember the basics of the body’s fluid compartments. TBW = WEIGHT x 0.5 (women) or 0.6 (men) TBW x 1/3 = ECF TBW x 2/3 = ICF ECF x 2/3 =...

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Renal function tests in a nutshell.

Renal Function Tests are a set of laboratary tests and analysis of Kidney function to detect and diagnose to observe the progress of renal disease. Here we deal with RFT in a nutshell.

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Clinical Quiz 2

Answer the following quiz by commenting below with question number and your choices.

The questions are drafted according to latest NEET format.

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High Ceiling Diuretics

Follow Loop diuretics are the most powerful of all diuretics, they termed “high ceiling”.The loop diuretics drugs act primary on the thick segment of the ascending loop of Henle, inhibiting the transport of sodium chloride out of the tubule into the interstitial tissue by inhibiting the Na+ / K+ / 2Cl- carrier in the luminal membrane. Loop diuretics abolish cortico medullary osmotic gradient and dicrease positive as well as negative free water clearance. By inhibiting Na+ / K+ / 2Cl- symporter , absorbtion of Na+ in loop of henle decreases.This unabsorbed Na+ reaches DT , where...

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Renal Failure – How to approach? – 1

Renal Failure – How to approach? An article by Dr. Bijoy Antony explaining how to approach Renal Failure in a clinical environment. The topic deals with basic pathology, clinical features and advanced management of Renal failure

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